No – dentures should be cleaned, if possible, after each meal. The best way is to remove them and rinse them. If one is able to, brushing the dentures with a wet tooth brush (no toothpaste!) is advised, as well as rinsing the mouth to clean it of any debris. If some natural teeth do remain, we suggest that you brush and floss them as your dentures may be secured in your mouth using your existing teeth. They are more important than ever to care for properly. Always soak dentures at night after brushing them. Over the counter cleaning agents are available. Keeping the dentures soaked protects them from warping. It is also much healthier to keep the teeth out overnight to avoid excessive pressure on the soft tissue and bone. Always remember to brush your tongue and lightly brush the gums with a soft toothbrush. Special denture brushes should be used on the dentures.